The University Hospital of Münster is one of the leading hospitals in Germany. Such a position cannot be achieved by size and medical successes alone. The individual commitment counts above all. We need your commitment so that even with little things we can achieve great things for our patients. There are many possibilities open for you so that you may develop with them.
The Institute of Molecular Tumor Biology at the Medical Faculty of the University of Münster invites applications on a limited contract of 3 years for a
PhD Student Position (gn*)
Part-Time with 65%
Salary according to TV-L
(*gn= gender neutral)
in the department of Molecular Stem Cell Biology, head Frank Rosenbauer, PhD (https://www.medizin.uni-muenster.de/imtb/rosenbauer-lab/).
Applicants are invited to join our research team at the Institute of Molecular Tumor Biology. Our group has a long-term interest in elucidating molecular mechanisms that control hematopoietic stem cell function and leukemia development by investigating transcription factors and epigenetic pathways (see for example Fischer et al. 2019 Nature Immunology, Schützmann et al. 2019 BLOOD and Riemke et al. 2016 EMBO Journal).
We are currently seeking a talented and highly motivated scientific fellow for a specific project on transcriptional and epigenetic regulation of the PU.1 transcription factor gene. PU.1 is the master regulator of myeloid cell differentiation and downregulation of PU.1 activity is a frequent event in myeloid leukemia. Understanding how PU.1 activity is controlled will help to understand mechanisms of leukemia development.
The candidate will use a novel CRISRP/Cas9-based method to investigate how chromatin looping regulates PU.1 expression. Candidates should have experience with tissue culture and standard molecular biology methods. Bioinformatical experience would be a plus. A good command of the English language is required.
We offer a productive and dynamic environment within a friendly team of experienced researchers.
For questions please contact Prof. Frank Rosenbauer, E-Mail: frank.rosenbauer(at)ukmuenster(dot)de
Applications should include a full CV, and the names of two referees. Please send applications until 09.10.2019 to bewerbung(at)ukmuenster(dot)de.
Applications of women are specifically invited. In case of similar qualification, competence and specific achievements, women will be considered on preferential terms within the framework of the legal possibilities. Handicapped candidates with equivalent qualifications will be given preference.