The Curvature-Dependent Self-Organization in Cellular Systems at University of Muenster, Germany, is offering at the earliest starting date a position limited to 3 years as a
PhD Student (gn*)
Salary according to German TV-L E13 (65%)
The Galic lab investigates the fundamental biological question how cells manage to coordinate shape, motion, as well as collective behavior in the absence of external signaling inputs. In particular, we are interested in understanding how receptor-independent signaling hubs yield self-organization at cellular membranes. To investigate this novel signaling principle, we take advantage of an interdisciplinary approach, combining state of the art cell biology, microscopy, image analysis and software-assisted methods.
Cellular behavior is strongly influenced by extracellular signals, such as polarized chemical gradients. Nevertheless, cells frequently encounter situations where such signals are absent. In this project, we aim to investigate how cells respond in such occasions. Specifically, we aim to answer (i) how spontaneously assembly of curvature-sensing proteins leads to cellular self-organization, and (ii) how this is used to maintain polarization needed for directed motion or cell shape changes. Insights from these studies are of high biomedical relevance, as it will provide new paradigms how cells optimize single (e.g. search efficiency, architecture) and collective (e.g. wound healing) behavior in a receptor-independent manner.
The prospective holder of the position will be working in the research group of Dr. Galic at the Institute of Medical Physics and Biophysics. We offer a well-equipped, international working environment, where talented and self-motivated students will find excellent opportunities to develop and pursue their personal scientific ideas.
You are an enthusiastic, ambitious scientist who is not afraid to work in an interdisciplinary, international team. You have a recent diploma or master degree in cell biology or a similar biomedical discipline. Experience in cell biology, microscopy and image analysis is welcome, but not required. A keen interest to learn these topics, however, is necessary. Good English and communication skills, as well as an interest in different scientific fields, are needed due to the interdisciplinary nature of the project and the group.
The position is available as of now. Following a probation phase (6 months), employment will be extended to a total of three years.
For further information please visit the homepage www.unimuenster.de/Cells-in-Motion/people/all/galic-m.php or contact Dr. Galic (Group leader): galic(at)uni-muenster(dot)de.
Applications including the reference number (04000) of the job post, a current resume with academic transcripts and at least one professional references should be sent until 16.10.2019 to bewerbung(at)ukmuenster(dot)de.