The University Hospital of Münster is one of the leading hospitals in Germany. Such a position cannot be achieved by size and medical successes alone. The individual commitment counts above all. We need your commitment so that even with little things we can achieve great things for our patients. There are many possibilities open for you so that you may develop with them.
The Institute of Physiological Chemistry and Pathobiochemistry, University Hospital of Münster, Münster, Germany offers a position, initially limited to 3 years, of a
PhD Student/Research Assistent (gn*)
Salary according to TV-L E13
We are currently looking for a motivated doctoral candidate with strong interest in interdisciplinary research in the area of synthetic biology at the interphase of chemistry and molecular biology. The project in particular involves the development of “Light controlled cell-cell contacts” as part of the ERC Starting Grant ARTIST (https://cordis.europa.eu/project/rcn/212072_en.html).
Specifically, we aim to control cell-cell interactions photochemically using proteins that respond to visible light as a reversible photoswitches. Cell-cell contacts are highly regulated during many biological processes including the organization in multicellular structures in the context of bottom-up tissue engineering. Therefore, manipulating cell-cell interactions with the photoswitchable proteins will allow for control how cells organize with respective to each other and self-sort into higher order architecture. Controlling cell-cell interactions with visible light is also attractive because light provides high spatial and temporal control, it is non-invasive and bio-orthogonal and also an important environmental signal. Such a platform will afford valuable insight into interactions between cells as well as synthetic surfaces and is applicable to the development of new bio-instructive materials.
Field of duties:
- Investigation of multicellular architectures
- Developing optogenetic tools for cell-cell adhesion
- Cell based assays (ELISA, Western blot, cell culture, fluorescence microscopy, image analysis)
- Master in Biochemistry, Biotechnology, Molecular biology or related fields
- High motivation, self-initiative and team-minded
- Good English skills
- Expertise in above mentioned tasks is advantageous
Please send your application together with the usual documents until 04.12.2019 via e-mail to Bewerbung(at)ukmuenster(dot)de.
Applications of women are specifically invited. In the case of similar qualifications, competence, and specific achievements, women will be considered on preferential terms within the framework of the legal possibilities. Handicapped candidates with equivalent qualifications will be given preference.