Postdoctoral Researcher in Neuroimmunology / Next-Generation-Sequencing (gn)

04859
Department of Neurology

The University Hospital of Münster is one of the leading hospitals in Germany. Such a position cannot be achieved by size and medical successes alone. The individual commitment counts above all. We need your commitment so that even with little things we can achieve great things for our patients. There are many possibilities open for you so that you may develop with them.

The Department of Neurology (Head: Prof. Dr. Heinz Wiendl), University Hospital of Muenster, Germany offers a position, initially limited to 3 years, of a

Postdoctoral Researcher in Neuroimmunology / Next-Generation-Sequencing (gn*)
Ref. 04859

Salary according to TV-L E13
Full-Time 100%


(*gn= gender neutral)

Our laboratory is dedicated to obtaining a better under¬standing of neuroimmunological diseases. We combine our experience in basic animal models and patient-focussed research with novel state-of-the-art Next Generation Sequencing (NGS) technologies to better understand nervous system autoimmunity (see e.g. PubMed IDs 32295886, 31937773).

We are an interdisciplinary team of biologists and physicians. The applicant will work within the Neuroimmunology lab of the Department as part of the established research group of PD Dr. Meyer zu Hörste.

In addition to various animal models and an extensive biobank of multiple sclerosis-derived specimen, we employ cell and molecular biology techniques such as flow cytometry, cell isolation and sorting, RT-PCR, Western blotting, cloning, ChIP-seq, RNA-seq, and confocal microscopy. We also routinely perform different single cell/nuclei RNA-sequencing (sc/snRNA-seq) methods. Specifically, we use 10x-based (and other) scRNA-seq techniques with or without CITE-seq in our department and provide the technology in a multitude of collaborative projects. We apply snRNA-seq on our large human biobank and have a special focus on antigen receptor sequencing. Bioinformatic analyses are performed either by us or by collaborators. We have a lively interaction with highly renowned groups in the field of immunology and neuroimmunology both nationally and internationally. This is reflected by our collaborations within the Sonderforschungsbereich „breaking barriers“, the Transregio SFB „Multiple Sclerosis“, and the Excellence Initiative Cells in Motion.

We are looking for a highly motivated postdoctoral scientist to better characterize local immune reactions in the nervous system by combining (single cell/nuclei) RNA-seq with animal models and translational projects.

The qualified candidate should have a Doctoral (Ph.D.) degree in biology, biochemistry, bioinformatics or a related scientific discipline. The candidate should be able to work independently but also to be a team player and share our passion for understanding nervous system autoimmunity. Hands-on experience in NGS methods will be most advantageous for the present position and such applicants will be given preference. Good written and oral communication skills in English are also required. Experience with animal models, flow cytometry or computational analysis tools will be beneficial but are not required. The ideal candidate will be interested in developing her/his own research profile including the ability to acquire independent third party funding.

Please send your application including a CV, a letter describing your motivation to work with us and 2 recommendation letters until 10.06.2020 electronically to PD Dr. Gerd Meyer zu Hörste (gerd.mzh(at)­uni-muenster(dot)­de) or to Personalgewinnung des Universitätsklinikums Münster, Bewerbermanagement, Domagkstraße 5, 48149 Münster or via e-mail to Bewerbung(at)­ukmuenster(dot)­de.

Applications of women are specifically invited. In the case of similar qualifications, competence, and specific achievements, women will be considered on preferential terms within the framework of the legal possibilities. Handicapped candidates with equivalent qualifications will be given preference.

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