The Immune-Microbiota Interactions Laboratory in the Department of Translational Rheumatology, Institute of Musculoskeletal Medicine at the University of Münster, Germany,is offering for a project on the role of the microbiome in autoimmunity at the earliest opportunity, initially limited to 3 years, a
Postdoctoral Scientist (gn*)
Salary according to German TV-L E13
Full-Time with 100%
The Group and Project:
The Immune-Microbiota Interactions Laboratoryinvestigates the cellular and molecular mechanisms of host-microbiota interactions in immune-mediated diseases. The group explores in particular basic mechanisms of immunologic tolerance in the context of the gut, skin, and other mucosal microbiota. The lab has previously investigated this field at Yale University (https://medicine.yale.edu/lab/kriegel/) before relocating to the University of Münster, Germany. The lab has recently identified several pathobionts in autoimmunity (Vieira et al, Science 2018; Greiling et al, Sci Transl Med 2018; Ruff et al, Cell Host Microbe 2019; Zegarra-Ruiz et al, Cell Host Microbe 2019) that are being studied in more depth. The lab is highly interdisciplinary and uses human tissue, organoid, and murine gnotobiotic approaches coupled with next-generation human microbiome sequencing to identify commensal triggers in autoimmunity and cancer. Techniques span a broad range from immunology, cell and molecular biology to microbiology including gnotobiotics and metagenomics.
- University degree with doctorate in biology, biomedicine or life sciences
- Profound knowledge of immunological techniques such as FACS, ELISAs, T/B cell stimulation assays
- Profound knowledge of in vitro and in vivo models
- Extensive experience in working with different knock out and transgenic animals, ideally also gnotobiotic research experience
- Independent, reliable and structured way of working with a strong sense of quality
- Flexibility, high team and communication skills and above-average motivation
- Ability to independently establish new methods and to independently and critically reflect on scientific data
- Excellent Internet and PC skills (Powerpoint, Excel, GraphPadPrism)
- Very good written and spoken English language skills
- Willingness to travel for several days with presentation of the results at national and international events
The Immune-Microbiota Interactions Laboratory is affiliated with the Section of Rheumatology and Clinical Immunology at the University Hospital of Münster and the Institute of Experimental Musculoskeletal Medicine. It is located adjacent to the Max-Planck Institute for Molecular Biomedicine and partly housed in the Center for Molecular Biology of Inflammation. For more information about the group see: https://www.medizin.uni-muenster.de/en/microbiome/startseite/
Applicants will have successfully completed a PhD or MD/PhD in a related field in one of the areas described in this posting.
For more information, please contact: Univ.-Prof. Dr. Martin Kriegel, martin.kriegel(at)ukmuenster(dot)de.
Please send your application including your CV including names of three referees, a short letter describing your motivation to apply, and the reference code until 14.10.2020 to Personalgewinnung des Universitätsklinikums Münster, Bewerbermanagement, Domagkstraße 5, 48149 Münster or via e-mail to Bewerbung(at)ukmuenster(dot)de.
Applications from female candidates are particularly encouraged. In the case of equal qualifications, competence and specific achievements, women will be considered on preferential terms within the framework of the legal possibilities unless reasons specific to an individual male candidate predominate. Handicapped candidates with equal qualifications will be given preference.
The University Hospital of Münster is one of the leading hospitals in Germany. Such a position cannot be achieved by size and medical successes alone. The individual commitment counts above all. We need your commitment so that even with little things we can achieve great things for our patients. There are many possibilities open for you so that you may develop with them.