Publikationen

Wilden JJ, van Krüchten A, Gieselmann L, Hrincius ER, Deinhardt-Emmer S, Haupt KF, Preugschas HF, Niemann S, Ludwig S and Ehrhardt C.
The influenza replication blocking inhibitor LASAG does not sensitize human epithelial cells for bacterial infections.
PLoS One. 2020; 15: e0233052. DOI: 10.1371/journal.pone.0233052

Treffon J, Chaves-Moreno D, Niemann S, Pieper DH, Vogl T, Roth J and Kahl BC. Importance of superoxide dismutases A and M for protection of Staphylococcus aureus in the oxidative stressful environment of cystic fibrosis airways.
Cell Microbiol. 2020; 22: e13158. DOI: 10.1111/cmi.13158

Shittu A, Deinhardt-Emmer S, Vas Nunes J, Niemann S, Grobusch MP and Schaumburg F.
Tropical pyomyositis: an update.
Trop Med Int Health. 2020; 25: 660-665. DOI: 10.1111/tmi.13395

Treffon, J,Chaves-Moreno, D,Niemann, S,Pieper, DH,Vogl, T,Roth, J and Kahl, BC. Importance of superoxide dismutases A and M for protection of Staphylococcus aureus in the oxidative stressful environment of cystic fibrosis airways.
Cell Microbiol. 2020; 22: e13158. DOI: 10.1111/cmi.13158

Schwarz C, Hoerr V, Tore Y, Hosker V, Hansen U, Van de Vyver H, Niemann  S, Kuhlmann MT, Jeibmann A, Wildgruber M and Faber C.
Isolating Crucial Steps in Induction of Infective Endocarditis With Preclinical Modeling of Host Pathogen Interaction.
Front Microbiol. 2020; 11: 1325. DOI: 10.3389/fmicb.2020.01325

Schaumburg F, Correa-Martinez CL, Niemann S, Kock R and Becker K.
Aetiology of traveller's diarrhea: A nested case-control study.
Travel Med Infect Dis. 2020; 37: 101696. DOI: 10.1016/j.tmaid.2020.101696

Fischer-Riepe, L,Daber, N,Schulte-Schrepping, J,Veras De Carvalho, BC,Russo, A,Pohlen, M,Fischer, J,Chasan, AI,Wolf, M,Ulas, T,Glander, S,Schulz, C,Skryabin, B,Wollbrink Dipl-Ing, A,Steingraeber, N,Stremmel, C,Koehle, M,Gartner, F,Vettorazzi, S,Holzinger, D,Gross, J,Rosenbauer, F,Stoll, M, Niemann, S,Tuckermann, J,Schultze, JL,Roth, J and Barczyk-Kahlert, K.
CD163 expression defines specific, IRF8-dependent, immune-modulatory macrophages in the bone marrow.
J Allergy Clin Immunol. 2020; 146: 1137-1151. DOI: 10.1016/j.jaci.2020.02.034

Herzog S ,Dach F, de Buhr N, Niemann S,Schlagowski J, Chaves-Moreno D, Neumann  C, Goretzko J, Schwierzeck V, Mellmann A, Dubbers A, Kuster P, Schultingkemper  H, Rescher U, Pieper DH, von Kockritz-Blickwede M and Kahl BC.
High Nuclease Activity of Long Persisting Staphylococcus aureus Isolates Within the Airways of Cystic Fibrosis Patients Protects Against NET-Mediated Killing.
Front Immunol. 2019; 10: 2552. DOI: 10.3389/fimmu.2019.02552

Hoerr V, Franz M, Pletz MW, Diab M, Niemann S, Faber C, Doenst T, Schulze PC, Deinhardt-Emmer S and Loffler B.
S. aureus endocarditis: Clinical aspects and experimental approaches.
Int J Med Microbiol. 2018 Aug;308(6):640-652. doi: 10.1016/j.ijmm.2018.02.004. Epub 2018 Feb 21. Review

van Kruchten A, Wilden JJ, Niemann S, Peters G, Loffler B, Ludwig S and Ehrhardt C.
Staphylococcus aureus triggers a shift from influenza virus-induced apoptosis to necrotic cell death.
FASEB J. 2018 May;32(5):2779-2793. doi: 10.1096/fj.201701006R. Epub 2018 Jan 11.

Niemann S, Bertling A, Brodde MF, Fender AC, Van de Vyver H, Hussain M, Holzinger D, Reinhardt D, Peters G, Heilmann C, Loffler B and Kehrel BE.
Panton-Valentine Leukocidin associated with S. aureus osteomyelitis activates platelets via neutrophil secretion products.
Sci Rep. 2018 Feb 1;8(1):2185. doi: 10.1038/s41598-018-20582-z.

Bruchhagen C, Jarick M, Mewis C, Hertlein T, Niemann S, Ohlsen K, Peters G, Planz O, Ludwig S and Ehrhardt C.
Metabolic conversion of CI-1040 turns a cellular MEK-inhibitor into an antibacterial compound.
Sci Rep. 2018 Jun 14;8(1):9114. doi: 10.1038/s41598-018-27445-7.

Van de Vyver H, Bovenkamp PR, Hoerr V, Schwegmann K, Tuchscherr L, Niemann S, Kursawe L, Grosse C, Moter A, Hansen U, Neugebauer U, Kuhlmann MT, Peters G, Hermann S and Loffler B.
A Novel Mouse Model of Staphylococcus aureus Vascular Graft Infection: Noninvasive Imaging of Biofilm Development in Vivo.
Am J Pathol. 2017 Feb;187(2):268-279. doi: 10.1016/j.ajpath.2016.10.005. Epub 2017 Jan 11.

Lebughe M, Phaku P, Niemann S, Mumba D, Peters G, Muyembe-Tamfum JJ, Mellmann A, Strauss L and Schaumburg F.
The Impact of the Staphylococcus aureus Virulome on Infection in a Developing Country: A Cohort Study.
Front Microbiol. 2017 Aug 29;8:1662. doi: 10.3389/fmicb.2017.01662. eCollection 2017.

Klemm C, Bruchhagen C, van Kruchten A, Niemann S, Loffler B, Peters G, Ludwig S and Ehrhardt C.
Mitogen-activated protein kinases (MAPKs) regulate IL-6 over-production during concomitant influenza virus and Staphylococcus aureus infection.
Sci Rep. 2017 Feb 14;7:42473. doi: 10.1038/srep42473.

Gruner MC, Niemann S, Faust A and Strassert CA.
Axially Decorated Si(IV) -phthalocyanines Bearing Mannose- or Ammonium-conjugated Siloxanes: Comparative Bacterial Labeling and Photodynamic Inactivation
Photochem Photobiol. 2017 Dec 29. doi: 10.1111/php.12881. [Epub ahead of print]

Wang J, Morita Y, Han B, Niemann S, Loffler B and Rudolph KL.
Per2 induction limits lymphoid-biased haematopoietic stem cells and lymphopoiesis in the context of DNA damage and ageing.
Nat Cell Biol. 2016 May;18(5):480-90. doi: 10.1038/ncb3342. Epub 2016 Apr 18.

Strobel M, Pfortner H, Tuchscherr L, Volker U, Schmidt F, Kramko N, Schnittler HJ, Fraunholz MJ, Loffler B, Peters G and Niemann S. Post-invasion events after infection with Staphylococcus aureus are strongly dependent on both the host cell type and the infecting S. aureus strain.
Clin Microbiol Infect. 2016 Sep;22(9):799-809. doi: 10.1016/j.cmi.2016.06.020. Epub 2016 Jul 5.

Galstyan A, Block D, Niemann S, Gruner MC, Abbruzzetti S, Oneto M, Daniliuc CG, Hermann S, Viappiani C, Schafers M, Loffler B, Strassert CA and Faust A.
Labeling and Selective Inactivation of Gram-Positive Bacteria Employing Bimodal Photoprobes with Dual Readouts.
Chemistry. 2016 Apr 4;22(15):5243-52. doi: 10.1002/chem.201504935. Epub 2016 Mar 1. Erratum in: Chemistry. 2016 Jun 27;22(27):9051.

Warnking K, Klemm C, Loffler B, Niemann S, van Kruchten A, Peters G, Ludwig S and Ehrhardt C.
Super-infection with Staphylococcus aureus inhibits influenza virus-induced type I IFN signalling through impaired STAT1-STAT2 dimerization.
Cell Microbiol. 2015 Mar;17(3):303-17. doi: 10.1111/cmi.12375. Epub 2014 Nov 19.

Tuchscherr L, Bischoff M, Lattar SM, Noto Llana M, Pfortner H, Niemann S, Geraci J, Van de Vyver H, Fraunholz MJ, Cheung AL, Herrmann M, Volker U, Sordelli DO, Peters G and Loffler B.
Sigma Factor SigB Is Crucial to Mediate Staphylococcus aureus Adaptation during Chronic Infections
PLoS Pathog. 2015 Apr 29;11(4):e1004870. doi: 10.1371/journal.ppat.1004870. eCollection 2015 Apr.

Kalinka J, Hachmeister M, Geraci J, Sordelli D, Hansen U, Niemann S, Oetermann S, Peters G, Loffler B and Tuchscherr L.
Staphylococcus aureus isolates from chronic osteomyelitis are characterized by high host cell invasion and intracellular adaptation, but still induce inflammation.
Int J Med Microbiol. 2014 Nov;304(8):1038-49. doi: 10.1016/j.ijmm.2014.07.013. Epub 2014 Jul 27.

Löffler B, Tuchscherr L, Niemann S, Peters G.
Staphylococcus aureus persistence in non-professional phagocytes.
Int J Med Microbiol. 2013 Dec 1. pii: S1438-4221(13)00184-7. doi: 10.1016/j.ijmm.2013.11.011.

Werdan K, Dietz S, Löffler B, Niemann S, Bushnaq H, Silber RE, Peters G, Müller-Werdan U.
Mechanisms of infective endocarditis: pathogen-host interaction and risk states.
Nat Rev Cardiol. 2014 Jan;11(1):35-50. doi: 10.1038/nrcardio.2013.174. Epub 2013 Nov 19.

Löffler B, Niemann S, Ehrhardt C, Horn D, Lanckohr C, Lina G, Ludwig S, Peters G.
Pathogenesis of Staphylococcus aureus nectrotizing pneumonia: the role of PVL and an influenza coinfection.
Expert Rev Anti Infect Ther. 2013 Oct;11(10):1041-51. doi: 10.1586/14787210.2013.827891. Epub 2013 Sep 27.

Niemann S, Ehrhardt C, Medina E, Warnking K, Tuchscherr L, Heitmann V, Ludwig S, Peters G, Löffler B.
Combined Action of Influenza Virus and Staphylococcus aureus Panton-Valentine Leukocidin Provokes Severe Lung Epithelium Damage.
J Infect Dis. 2012 Oct; 206(7) : 1138-48. Epub 2012 Jul 26

Holzinger D, Gieldon L, Mysore V, Nippe N, Taxman DJ, Duncan JA, Broglie PM, Marketon K, Austermann J, Vogl T, Foell D, Niemann S, Peters G, Roth J, Löffler B.
Staphylococcus aureus Panton-Valentine leukocidin induces an inflammatory response in human phagocytes via the NLRP3 inflammasome.
J Leukoc Biol. 2012 Aug 14. [Epub ahead of print]

Bertling, A,Niemann, S,Hussain, M,Holbrook, L,Stanley, RG,Brodde, MF,Pohl, S,Schifferdecker, T,Roth, J,Jurk, K,Muller, A,Lahav, J,Peters, G,Heilmann, C,Gibbins, JM and Kehrel, BE.
Staphylococcal extracellular adherence protein induces platelet activation by stimulation of thiol isomerases.
Arterioscler Thromb Vasc Biol. 2012; 32: 1979-1990. DOI:10.1161/ATVBAHA.112.246249

Tuchscherr L, Medina E, Hussain M, Völker W, Heitmann V, Niemann S, Holzinger D, Roth J, Proctor RA, Becker K, Peters G, Löffler B.
Staphylococcus aureus  phenotype switching: an effective bacterial strategy to escape host immune response and establish a chronic infection.
EMBO Mol Med. 2011 Mar; 3(3) : 129-41

Bertling A, Niemann S, Uekotter A, Fegeler W, Lass-Florl C, von Eiff C and Kehrel, BE. Candida albicans and its metabolite gliotoxin inhibit platelet function via interaction with thiols.
Thromb Haemost. 2010; 104: 270-278. DOI: 10.1160/TH09-11-0769

Niemann, S,Kehrel, BE,Heilmann, C,Rennemeier, C,Peters, G and Hammerschmidt, S. Pneumococcal association to platelets is mediated by soluble fibrin and supported by thrombospondin-1.
Thromb Haemost. 2009; 102: 735-742. DOI: 10.1160/TH09-01-0049

Rennemeier, C,Hammerschmidt, S,Niemann, S,Inamura, S,Zahringer, U and Kehrel, BE. Thrombospondin-1 promotes cellular adherence of gram-positive pathogens via recognition of peptidoglycan.
FASEB J. 2007; 21: 3118-3132. DOI: 10.1096/fj.06-7992com

Niemann, S,Spehr, N,Van Aken, H,Morgenstern, E,Peters, G,Herrmann, M and Kehrel, BE.
Soluble fibrin is the main mediator of Staphylococcus aureus adhesion to platelets. Circulation. 2004; 110: 193-200. DOI: 10.1161/01.CIR.0000134486.93030.E7

Heilmann, C,Niemann, S,Sinha, B,Herrmann, M,Kehrel, BE and Peters, G. Staphylococcus aureus fibronectin-binding protein (FnBP)-mediated adherence to platelets, and aggregation of platelets induced by FnBPA but not by FnBPB.
J Infect Dis. 2004; 190: 321-329. DOI: 10.1086/421914