Translational Inflammation Research

Kuehn J, Schleifenbaum S, Hendling M, Siebenhandl S, Krainer J, Fuehner S, Hellige A, Park C, Hinze C, Wittkowski H, Holzinger D, Thurner L, Weinhäusel A, Foell D, Kessel C. Aberrant naive CD4+ T cell differentiation in systemic juvenile idiopathic arthritis is committed to B cell help. Arthritis Rheumatol. 2022 Nov 21. doi: 10.1002/art.42409. Online ahead of print.PMID: 36409585

Thurner L*, Kessel C*, …, Pfeifer J* and Klingel K*. IL-1Ra antibodies in myocarditis after SARS-CoV-2 vaccination. N Engl J Med. 2022 Oct 20;387(16):1524-1527.*equal contribution (Mehr Infos) 

Pfeifer J*, Thurner B*, Kessel C*, …, and Thurner L. Autoantibodies against interleukin-1 receptor antagonist in multisystem inflammatory syndrome in children: a multicentre, retrospective, cohort study. Lancet Rheumatol. 2022 May;4(5):e329-e337. *equal contribution (Mehr Infos)

Kessel C, Vollenberg R, ..., Foell D, Tepasse PR. Discrimination of COVID-19 from inflammation-induced cytokine storm syndromes by disease-related blood biomarkers. Arthritis Rheumatol. 2021 Oct;73(10):1791-1799. doi: 10.1002/art.41763. Epub 2021 Sep 3

Kessel C, ..., Holzinger D. Definition and validation of serum biomarkers for optimal differentiation of hyperferritinemic cytokine storm conditions in children: a multi-centre retrospective cohort study. The Lancet Rheumatol, 2021; 3: e563–e573

Verweyen E, ..., Kessel C. Synergistic Signaling of TLR and IFNα/β Facilitates Escape of IL-18 Expression from Endotoxin Tolerance. Am J Respir Crit Care Med. 2020 Mar 1;201(5):526-539. doi: 10.1164/rccm.201903-0659OC.

Related editorial to Verweyen et al.: LaRiviere WB, Schmidt EP. Using the Extremes of Human Inflammation to Understand the Transcriptional Control of IL-18. Am J Respir Crit Care Med. 2020 Mar 1;201(5):503-504. doi: 10.1164/rccm.201912-2322ED.

Armaroli G, ..., Kessel C. Monocyte-Derived Interleukin-1β As the Driver of S100A12-Induced Sterile Inflammatory Activation of Human Coronary Artery Endothelial Cells: Implications for the Pathogenesis of Kawasaki Disease. Arthritis Rheumatol, 2019;71(5):792-804

Kessel C, Fuehner S, Zell J, Zimmermann B, Drewianka S, Brockmeyer S, Holzinger D, Hinze C, Wittkowski H, Foell D. Calcium and zinc tune autoinflammatory TLR4-signaling by S100A12. JACI, 2018; 142(4):1370-1373

Kessel C, Lippitz K, Weinhage T, Hinze C, Wittkowski H, Holzinger D, Fall N, Grom AA, Gruen N, Foell D. Proinflammatory Cytokine Environments Can Drive Interleukin-17 Overexpression by γ/δ T Cells in Systemic Juvenile Idiopathic Arthritis. Arthritis Rheumatol, 2017; 69(7): 1480-1494

DGRH, Berlin, 2022: GKJR-Forschungspreis für Julia Kühn

PReS/CARRA collaborative research award für Christoph Kessel und Grant Schubert (Cincinnati, OH, USA):

https://www.medizin.uni-muenster.de/fakultaet/news/gemeinsam-gegen-kinder-rheuma-deutsch-amerikanische-forschungskooperation-erarbeitet-biomarker-standards.html

https://www.pres.eu/research/CARRA-PRES.html

DGRH, Dresden, 2019: GKJR-Forschungspreis für Emely Verweyen

PReS young investigator award C. Kessel:

www.medizin.uni-muenster.de/fakultaet/news/kinderrheumatologie-europaeischer-nachwuchswissenschaftlerpreis-fuer-dr-christoph-kessel/

GKJR-Forschungspreis für Giulia Armaroli

gkjr.de/fileadmin/user_upload/Dokumente/GKJRintern/nachrichten/ar_06_17_gkjr.pdf

Web-Profile:

PReS sJIA/MAS working party: www.pres.eu/committee-and-wp/working-parties.html

https://loop.frontiersin.org/people/470832/overview

www.researchgate.net/profile/Christoph_Kessel