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Kinderherzchirurgie

Kinderherzchirurgie

Forschung

Unsere Sektion führt eigene wissenschaftliche Projekte durch und beteiligt sich an überregionalen/multizentrischen Studien. 

Klinische Forschung

Publikationen

Aktuelle klinisch-wissenschaftliche Vorhaben

TitelA prospective randomized, single-blind, multicenter phase II study comparing two methods of cardioplegia in cardiac surgery due to congenital heart malformation in children: Custodiol-N versus Custodiol
Beschreibung                                  In dieser randomisiert-kontrollierten Studie wird die Myokardprotektion mittels Custodiol-N (Interventionsgruppe) mit der Myokardprotektion mittels Custodiol (Kontrollgruppe) verglichen.
Ansprechpartner     Priv.-Doz. Dr. Philippe Grieshaber
RegistrierungEU trial number 2024-511517-38-00
TitelHistomorphologische Untersuchungen von explantierten Materialien bei herzchirurgischen Zweiteingriffen – Beobachtung von reaktiven Gewebeveränderungen nach Patch-, Homograft- und Contegragraftimplantation
Beschreibung                                                                     Wir untersuchen in unserem Labor Gewebeproben von Materialien, die für Korrektureingriff am Herzen benötigt werden, aber aufgrund ihrer begrenzten Haltbarkeit nicht selten ausgetauscht werden müssen. Um das bestmögliche Material zu identifizieren, werden Analysen hinsichtlich Entzündungs-/Immunreaktionen und degenerativer Veränderungen durchgeführt.
AnsprechpartnerinPriv.-Doz. Dr. med. Sabrina Martens, MBA

Publikationen

  • Peivandi AD, Holtkamp M, Rave H, Linsen L, Martens S, Müller KM, Karst U, Martens S. Rapid versus slow degeneration and complications of biomaterials in patients with congenital heart disease. Cardiovasc Pathol. 2024 Dec 31;75:107712. doi: 10.1016/j.carpath.2024.107712. Epub ahead of print. PMID: 39746622.
     
  • Killinger K, Riedel F, Fiedler MO, Müller T, Wallwiener M, Wallwiener S, Elsässer M, Weigand MA, Böckler D, Erhart P, Grieshaber P, Hackert T, Germann G, Scholz AS. Dilemma Diagnosis Between Pulmonary Embolism and Amniotic Fluid Embolism During First Stage of Labor-A Case Report. Clin Case Rep. 2024 Nov 15;12(11):e9579. doi: 10.1002/ccr3.9579. PMID: 39555203; PMCID: PMC11567775.
     
  • Grieshaber P, Schneller A, Fonseca-Escalante E, Farag M, Krey R, Czundel A, Jaschinski C, Karck M, Gorenflo M, Loukanov T. A Low-Cost Workflow to Generate Virtual and Physical Three-Dimensional Models of Cardiac Structures. World J Pediatr Congenit Heart Surg. 2025 Jan;16(1):107-113. doi: 10.1177/21501351241293305. Epub 2024 Nov 14. PMID: 39539235; PMCID: PMC11645847.
     
  • Grieshaber P, Jaschinski C, Farag M, Fonseca-Escalante E, Gorenflo M, Karck M, Loukanov T. Surgical Treatment of Atrial Septal Defects. Rev Cardiovasc Med. 2024 Sep 29;25(10):350. doi: 10.31083/j.rcm2510350. PMID: 39484126; PMCID: PMC11522766.
     
  • Peivandi AD, Martens S, Gion A, Rukosujew A, Martens S. Pulmonary valve replacement-A 10-year single-center surgical experience in ACHD patients. PLoS One. 2024 Oct 4;19(10):e0310700. doi: 10.1371/journal.pone.0310700. PMID: 39365810; PMCID: PMC11452008.
     
  • Farag M, Escalante EF, Czundel A, Steeg C, Shelton B, Krey R, Grieshaber P, Loukanov T. Aortic uncrossing of the left circumflex aorta. Multimed Man Cardiothorac Surg. 2024 Jul 9;2024. doi: 10.1510/mmcts.2024.061. PMID: 38979788. Grieshaber P, Farag M, Fonseca-Escalante E, Loukanov T. Perfusion During Aortic Arch Surgery-Keep it Physiologic! World J Pediatr Congenit Heart Surg. 2024 Mar;15(2):251. doi: 10.1177/21501351231221427. Epub 2024 Jan 9. PMID: 38196329; PMCID: PMC10938473. 

 

  • Martens S, Tie H, Kehl HG, Tjan TD, Scheld HH, Martens S, Hoffmeier A. Heart transplantation surgery in children and young adults with congenital heart disease. J Cardiothorac Surg. 2023 Nov 27;18(1):342. doi: 10.1186/s13019-023-02461-5. PMID: 38012741; PMCID: PMC10683181.
     
  • Tie H, Li Z, Welp H, Guha A, Caraballo C, Deschka H, Shi R, Zheng X, Martens S, Sindermann J, Chen D, Wu Q, Martens S. Calcium channel blockers and clinical outcomes in patients with continuous-flow left ventricular assist devices. ESC Heart Fail. 2024 Feb;11(1):271-281. doi: 10.1002/ehf2.14576. Epub 2023 Nov 15. PMID: 37967837; PMCID: PMC10804166.
     
  • Tie H, Li T, Huang B, Mariani S, Li T, van Bussel BCT, Wu Q, Pei J, Welp H, Martens S, Li Z, Shi R, Zhu J, Luo S, Lichtenberg A, Aubin H, Boeken U, Lorusso R, Chen D. Presence and impact of anemia in patients supported with left ventricular assist devices. J Heart Lung Transplant. 2023 Sep;42(9):1261-1274. doi: 10.1016/j.healun.2023.04.013. Epub 2023 Apr 29. PMID: 37127070.
     
  • Peivandi AD, Martens S, Asfour B, Martens S. Grafts and Patches: Optimized but Not Optimal Materials for Congenital Heart Surgery. Pediatr Cardiol. 2023 Jun;44(5):996-1002. doi: 10.1007/s00246-023-03153-6. Epub 2023 Apr 10. PMID: 37038028; PMCID: PMC10224861.
     
  • Uhl S, Grieshaber P, Arnold R, Loukanov T, Gorenflo M. Impact of hybrid procedure on pulmonary arterial dimensions and right ventricular load after biventricular repair. J Cardiothorac Surg. 2023 Feb 7;18(1):65. doi: 10.1186/s13019-023-02162-z. PMID: 36750898; PMCID: PMC9906912.
     
  • Bleiziffer S, Hanke J, Färber G, Martens S, Mohr R, Keuder A, Cleuziou J, Niethard M. Operieren in der Schwangerschaft: Ein Update der Rechts- und Datenlage für die Herzchirurgie [Operating during pregnancy]. Z Herz Thorax Gefasschir. 2023;37(1):41-44. German. doi: 10.1007/s00398-022-00550-6. Epub 2022 Dec 21. PMID: 36570590; PMCID: PMC9768757.
     
  • Tie H, Zhu J, Akin S, Allen LA, Huang B, Martens S, Welp H, Simpkin A, Shi R, Wu Q, Soliman O, Caliskan K, Chen D. Characteristics and Outcome of Patients With a History of Cancer Undergoing Durable Left Ventricular Assist Device Implantation. Circ Heart Fail. 2023 Feb;16(2):e009772. doi: 10.1161/CIRCHEARTFAILURE.122.009772. Epub 2022 Nov 14. PMID: 36373549.
     
  • Martens S, Schranz D, Kehl HG, Kiski D. Way of Planning a Complex Interventional Treatment with Support of a 3-Dimensional Printed Heart Model in a Patient with Interrupted Aortic Arch Type A. Pediatr Cardiol. 2023 Mar;44(3):732-735. doi: 10.1007/s00246-022-03025-5. Epub 2022 Oct 28. PMID: 36307564; PMCID: PMC9950167.
     
  • Martens S, Tie H, Scheld HH, Martens S, Hoffmeier A. Quality of Life After Heart Transplantation for Congenital Heart Defect. Transpl Int. 2022 Oct 6;35:10480. doi: 10.3389/ti.2022.10480. PMID: 36274813; PMCID: PMC9583515.
     
  • Möbius A, Grieshaber P, Turra J, Riesterer D, Zaradzki M, Soso P, Hatiboglu G, Hohenfellner M, Warnecke G, Tochtermann U. Cavoatrial hypernephroma resection on cardiopulmonary bypass: Mild/normo-versus moderate hypothermia. Perfusion. 2023 Nov;38(8):1644-1651. doi: 10.1177/02676591221128143. Epub 2022 Sep 20. PMID: 36125270; PMCID: PMC10612369.
  • Poppenborg F, Martens S, Martens S. The influence of glutaraldehyde on the microscopic structure of human pericardium. Cardiovasc Pathol. 2022 Nov- Dec;61:107457. doi: 10.1016/j.carpath.2022.107457. Epub 2022 Jul 20. PMID: 35870786.
     
  • Tie H, Shi R, Welp H, Martens S, Li Z, Sindermann JR, Martens S. Tricuspid Valve Surgery in Patients Receiving Left Ventricular Assist Devices. Thorac Cardiovasc Surg. 2022 Sep;70(6):475-481. doi: 10.1055/s-0042-1743594. Epub 2022 Jul 4. PMID: 35785810.
     
  • Grieshaber P, Merbecks M, Jaschinski C, Fonseca E, Arnold R, Karck M, Gorenflo M, Loukanov T. Surgical Treatment Following Stent Angioplasty for High- Risk Neonates With Critical Coarctation of the Aorta. World J Pediatr Congenit Heart Surg. 2022 Jul;13(4):426-435. doi: 10.1177/21501351221099933. PMID: 35757941; PMCID: PMC9243453.
     
  • Peivandi AD, Martens S, Heitplatz B, Guseva A, Mueller KM, Martens S. Industrial Processing Induces Pericardial Patch Degeneration. Front Surg. 2022 May 27;9:881433. doi: 10.3389/fsurg.2022.881433. PMID: 35711712; PMCID: PMC9195290.
     
  • Tie H, Shi R, Welp H, Martens S, Li Z, Sindermann J, Martens S. C-reactive protein predicts early clinical outcomes and long-term mortality after left ventricular assisted device. Int J Artif Organs. 2022 May;45(5):497-505. doi: 10.1177/03913988221088614. Epub 2022 Apr 7. PMID: 35388731.
     
  • Kuehn C, Ruemke S, Rellecke P, Lichtenberg A, Joskowiak D, Hagl C, Hassan M, Leyh RG, Erler S, Garbade J, Eifert S, Grieshaber P, Boening A, Doenst T, Velichkov I, Madej T, Knaut M, Hain A, Burger H. Wearable cardioverter defibrillator multicentre experience in a large cardiac surgery cohort at transient risk of sudden cardiac death. Eur J Cardiothorac Surg. 2022 May 2;61(5):1031-1040. doi: 10.1093/ejcts/ezac086. PMID: 35174386; PMCID: PMC9070494.
     
  • Heer T, von Scheidt M, Boening A, Heyken C, Gusmini F, de Waha A, Kuna C, Fach A, Grothusen C, Oberhoffer M, Knosalla C, Walther T, Danner BC, Misfeld M, Wimmer-Greinecker G, Siepe M, Grubitzsch H, Joost A, Schaefer A, Conradi L, Cremer J, Hamm C, Lange R, Radke PW, Schulz R, Laufer G, Grieshaber P, Attmann T, Schmoeckel M, Meyer A, Ziegelhöffer T, Hambrecht R, Sandner SE, Kastrati A, Schunkert H, Zeymer U. Prognostic impact of secondary prevention after coronary artery bypass grafting-insights from the TiCAB trial. Eur J Cardiothorac Surg. 2022 Aug 3;62(3):ezac048. doi: 10.1093/ejcts/ezac048. PMID: 35138350.
     
  • von Groote TC, Ostermann M, Forni LG, Meersch-Dini M, Zarbock A; PrevAKI Investigators. The AKI care bundle: all bundle components are created equal-are they? Intensive Care M
  • Tie H, Welp H, Martens S, Seiler M, Albers P, Mueller KM, Li Z, Martens S. Impact of cardiac fibrosis and collagens on right ventricular failure and acute kidney injury in patients after continuous-flow left ventricular assist devices. Interact Cardiovasc Thorac Surg. 2021 Nov 22;33(6):969-977. doi: 10.1093/icvts/ivab180. PMID: 34252191; PMCID: PMC8923418.
     
  • Veitinger AB, Komguem A, Assling-Simon L, Heep M, Schipke J, Mühlfeld C, Niemann B, Grieshaber P, Boengler K, Böning A. Cardioprotection with esmolol- based cardioplegia for non-infarcted and infarcted rat hearts. Eur J Cardiothorac Surg. 2021 Oct 22;60(4):908-917. doi: 10.1093/ejcts/ezab117. PMID: 33709143.
     
  • Zarbock A, Küllmar M, Ostermann M, Lucchese G, Baig K, Cennamo A, Rajani R, McCorkell S, Arndt C, Wulf H, Irqsusi M, Monaco F, Di Prima AL, García Alvarez M, Italiano S, Miralles Bagan J, Kunst G, Nair S, L'Acqua C, Hoste E, Vandenberghe W, Honore PM, Kellum JA, Forni LG, Grieshaber P, Massoth C, Weiss R, Gerss J, Wempe C, Meersch M. Prevention of Cardiac Surgery-Associated Acute Kidney Injury by Implementing the KDIGO Guidelines in High-Risk Patients Identified by Biomarkers: The PrevAKI-Multicenter Randomized Controlled Trial. Anesth Analg. 2021 Aug 1;133(2):292-302. doi: 10.1213/ANE.0000000000005458. PMID: 33684086.
     
  • Angeli E, Martens S, Careddu L, Petridis FD, Quarti AG, Ciuca C, Balducci A, Fabozzo A, Ragni L, Donti A, Gargiulo GD. Myocardial oxygen consumption during histidine-tryptophan-ketoglutarate cardioplegia in young human hearts. Interact Cardiovasc Thorac Surg. 2021 Jan 22;32(2):319-324. doi: 10.1093/icvts/ivaa262. PMID: 33398332; PMCID: PMC8906757.
     
  • Oswald I, Boening A, Pons-Kuehnemann J, Grieshaber P. Wound Infection after CABG Using Internal Mammary Artery Grafts: A Meta-Analysis. Thorac Cardiovasc Surg. 2021 Oct;69(7):639-648. doi: 10.1055/s-0040-1713662. Epub 2020 Aug 13. PMID: 32791543.
     
  • Gehron J, Bongert M, Böning A, Grieshaber P; EMPACS (Exploration of the mixing phenomena during interaction of internal and external circulations) study group. Should we be concerned about combining extracorporeal support and mechanical left ventricular unloading?†. Eur J Cardiothorac Surg. 2021 Jan 4;59(1):286-287. doi: 10.1093/ejcts/ezaa225. PMID: 32772091.
  • Gehron J, Schuster M, Rindler F, Bongert M, Böning A, Krombach G, Fiebich M, Grieshaber P; EMPACS (Exploration of the mixing phenomena during interaction of internal and external circulations) study group. Watershed phenomena during extracorporeal life support and their clinical impact: a systematic in vitro investigation. ESC Heart Fail. 2020 Aug;7(4):1850-1861. doi: 10.1002/ehf2.12751. Epub 2020 Jun 12. PMID: 32530129; PMCID: PMC7373893.
     
  • Weidenmann V, Robinson NB, Rong LQ, Hameed I, Naik A, Morsi M, Grieshaber P, Böning A, Girardi LN, Gaudino M. Diagnostic dilemma of perioperative myocardial infarction after coronary artery bypass grafting: A review. Int J Surg. 2020 Jul;79:76-83. doi: 10.1016/j.ijsu.2020.05.036. Epub 2020 May 19. PMID: 32442689; PMCID: PMC7853700.
     
  • Küllmar M, Massoth C, Ostermann M, Campos S, Grau Novellas N, Thomson G, Haffner M, Arndt C, Wulf H, Irqsusi M, Monaco F, Di Prima A, Garcia Alvarez M, Italiano S, Cegarra SanMartin V, Kunst G, Nair S, L'Acqua C, Hoste EAJ, Vandenberghe W, Honore PM, Kellum J, Forni L, Grieshaber P, Weiss R, Gerss J, Wempe C, Meersch M, Zarbock A. Biomarker-guided implementation of the KDIGO guidelines to reduce the occurrence of acute kidney injury in patients after cardiac surgery (PrevAKI-multicentre): protocol for a multicentre, observational study followed by randomised controlled feasibility trial. BMJ Open. 2020 Apr 6;10(4):e034201. doi: 10.1136/bmjopen-2019-034201. PMID: 32265240; PMCID: PMC7245412.
     
  • Grieshaber P, Oswald I, Albert M, Reents W, Zacher M, Roth P, Niemann B, Dörr O, Krüger T, Nef H, Sodah A, Hamm C, Schlensak C, Diegeler A, Sedding D, Franke U, Boening A. Risk of perioperative coronary stent stenosis or occlusion in patients with previous percutaneous coronary intervention undergoing coronary artery bypass grafting surgery. Eur J Cardiothorac Surg. 2020 Jun 1;57(6):1122-1129. doi: 10.1093/ejcts/ezaa003. PMID: 32011670.
     
  • Küllmar M, Weiß R, Ostermann M, Campos S, Grau Novellas N, Thomson G, Haffner M, Arndt C, Wulf H, Irqsusi M, Monaco F, Di Prima AL, García-Alvarez M, Italiano S, Felipe Correoso M, Kunst G, Nair S, L'Acqua C, Hoste E, Vandenberghe W, Honore PM, Kellum JA, Forni L, Grieshaber P, Wempe C, Meersch M, Zarbock A. A Multinational Observational Study Exploring Adherence With the Kidney Disease: Improving Global Outcomes Recommendations for Prevention of Acute Kidney Injury After Cardiac Surgery. Anesth Analg. 2020 Apr;130(4):910-916. doi: 10.1213/ANE.0000000000004642. PMID: 31922998.
     
  • Boening A, Hinke M, Heep M, Boengler K, Niemann B, Grieshaber P. Cardiac surgery in acute myocardial infarction: crystalloid versus blood cardioplegia - an experimental study. J Cardiothorac Surg. 2020 Jan 8;15(1):4. doi: 10.1186/s13019-020-1058-9. PMID: 31915024; PMCID: PMC6950911.
     
  • Jiang Q, Li H, Huang X, Yu L, Lueck S, Hu S. Postnatal exposure to hypobaric hypoxia and its impact on inflammation and injury indexes after a cardiac valve procedure. Interact Cardiovasc Thorac Surg. 2020 Dec 7;31(6):789-795. doi: 10.1093/icvts/ivaa188. PMID: 33118008.
  • Niemann B, Dominik E, Rohrbach S, Grieshaber P, Roth P, Böning A. The Same is Not the Same: Device Effect during Bipolar Radiofrequency Ablation of Atrial Fibrillation. Thorac Cardiovasc Surg. 2021 Mar;69(2):124-132. doi: 10.1055/s-0039-1698402. Epub 2019 Oct 11. PMID: 31604356.
     
  • Kube T, Meyer J, Grieshaber P, Moosdorf R, Böning A, Rief W. Patients' pre- and postoperative expectations as predictors of clinical outcomes six months after cardiac surgery. Psychol Health Med. 2020 Aug;25(7):781-792. doi: 10.1080/13548506.2019.1659986. Epub 2019 Aug 27. PMID: 31455096.
     
  • Schunkert H, Boening A, von Scheidt M, Lanig C, Gusmini F, de Waha A, Kuna C, Fach A, Grothusen C, Oberhoffer M, Knosalla C, Walther T, Danner BC, Misfeld M, Zeymer U, Wimmer-Greinecker G, Siepe M, Grubitzsch H, Joost A, Schaefer A, Conradi L, Cremer J, Hamm C, Lange R, Radke PW, Schulz R, Laufer G, Grieshaber P, Pader P, Attmann T, Schmoeckel M, Meyer A, Ziegelhöffer T, Hambrecht R, Kastrati A, Sandner SE. Randomized trial of ticagrelor vs. aspirin in patients after coronary artery bypass grafting: the TiCAB trial. Eur Heart J. 2019 Aug 1;40(29):2432-2440. doi: 10.1093/eurheartj/ehz185. PMID: 31145798.
     
  • Grieshaber P, Arneth B, Steinsberger F, Niemann B, Oswald I, Renz H, Böning A. Influence of Left Atrial Appendage Amputation on Natriuretic Peptides-A Randomized Controlled Trial. Thorac Cardiovasc Surg. 2021 Mar;69(2):117-123. doi: 10.1055/s-0039-1683955. Epub 2019 Mar 31. PMID: 30929250.
     
  • Bongert M, Gehron J, Geller M, Böning A, Grieshaber P. Cannula position and Bernoulli effect contribute to leg malperfusion during extracorporeal life support with femoral arterial cannulation-an in silico simulation study†. Interact Cardiovasc Thorac Surg. 2019 Aug 1;29(2):312–319. doi: 10.1093/icvts/ivz048. Epub 2019 Mar 15. PMID: 30879059.
     
  • Grieshaber P, Möller S, Arneth B, Roth P, Niemann B, Renz H, Böning A. Predicting Cardiac Surgery-Associated Acute Kidney Injury Using a Combination of Clinical Risk Scores and Urinary Biomarkers. Thorac Cardiovasc Surg. 2020 Aug;68(5):389-400. doi: 10.1055/s-0039-1678565. Epub 2019 Feb 11. PMID: 30743275.
     
  • Gehron J, Zirbes J, Bongert M, Schäfer S, Fiebich M, Krombach G, Böning A, Grieshaber P; EMPACS (Exploration of the mixing phenomena during interaction of internal and external circulations) study group. Development and Validation of a Life-Sized Mock Circulatory Loop of the Human Circulation for Fluid-Mechanical Studies. ASAIO J. 2019 Nov/Dec;65(8):788-797. doi: 10.1097/MAT.0000000000000880. PMID: 30281544.
     
  • Peivandi AD, Seiler M, Mueller KM, Martens S, Malec E, Asfour B, Lueck S. Elastica degeneration and intimal hyperplasia lead to Contegra® conduit failure. Eur J Cardiothorac Surg. 2019 Dec 1;56(6):1154-1161. doi: 10.1093/ejcts/ezz199. PMID: 31280306.
     
  • Lueck S, Bormann E, Rellensmann K, Martens S, Rukosujew A. Impact of additional tricuspid valve annuloplasty in TOF patients undergoing pulmonary valve replacement. J Cardiovasc Surg (Torino). 2019 Apr;60(2):268-273. doi: 10.23736/S0021-9509.18.10385-5. Epub 2018 May 22. PMID: 29786408.
  • Roth P, Stella J, Niemann B, Grieshaber P, Roehrig R, Böning A. Fibrin- Coated Collagen Fleece Seems to Prevent Sternal Instability after Cardiac Surgery: A Matched Pair Data Analysis. Thorac Cardiovasc Surg. 2020 Dec;68(8):737-742. doi: 10.1055/s-0038-1667326. Epub 2018 Aug 28. PMID: 30153697.
     
  • Angeli E, Lueck S, Gargiulo GD. Different strategies of myocardial protection: the age of perfectionism. J Thorac Dis. 2018 Mar;10(3):1211-1213. doi: 10.21037/jtd.2018.02.37. PMID: 29707268; PMCID: PMC5906289.
     
  • Grieshaber P, Schneider T, Oster L, Orhan C, Roth P, Niemann B, Böning A. Prophylactic intra-aortic balloon counterpulsation before surgical myocardial revascularization in patients with acute myocardial infarction. Perfusion. 2018 Jul;33(5):390-400. doi: 10.1177/0267659118760384. Epub 2018 Feb 18. PMID: 29457560.
     
  • Boening A, Assling-Simon L, Heep M, Boengler K, Niemann B, Schipke J, Mühlfeld C, Grieshaber P. Blood cardioplegia for cardiac surgery in acute myocardial infarction: rat experiments with two widely used solutions. Interact Cardiovasc Thorac Surg. 2018 Jul 1;27(1):88-94. doi: 10.1093/icvts/ivy011. PMID: 29452370.
     
  • Boening A, Assling-Simon L, Heep M, Boengler K, Niemann B, Grieshaber P. Buckberg's blood cardioplegia for protection of adult and senile myocardium in a rat in vitro model of acute myocardial infarction. Exp Gerontol. 2018 Apr;104:98-104. doi: 10.1016/j.exger.2018.02.003. Epub 2018 Feb 10. PMID: 29432894.
     
  • Grieshaber P, Heim N, Herzberg M, Niemann B, Roth P, Boening A. Active Chest Tube Clearance After Cardiac Surgery Is Associated With Reduced Reexploration Rates. Ann Thorac Surg. 2018 Jun;105(6):1771-1777. doi: 10.1016/j.athoracsur.2018.01.002. Epub 2018 Jan 31. PMID: 29382509.
     
  • Parigi SM, Czarnewski P, Das S, Steeg C, Brockmann L, Fernandez-Gaitero S, Yman V, Forkel M, Höög C, Mjösberg J, Westerberg L, Färnert A, Huber S, Jacobs T, Villablanca EJ. Flt3 ligand expands bona fide innate lymphoid cell precursors in vivo. Sci Rep. 2018 Jan 9;8(1):154. doi: 10.1038/s41598-017-18283-0. PMID: 29317685; PMCID: PMC5760642.
     
  • Grieshaber P, Oster L, Schneider T, Johnson V, Orhan C, Roth P, Niemann B, Böning A. Total arterial revascularization in patients with acute myocardial infarction - feasibility and outcomes. J Cardiothorac Surg. 2018 Jan 5;13(1):2. doi: 10.1186/s13019-017-0691-4. PMID: 29304874; PMCID: PMC5755408.
     
  • Uhle F, Castrup C, Necaev AM, Grieshaber P, Lichtenstern C, Weigand MA, Böning A. Inflammation and Its Consequences After Surgical Versus Transcatheter Aortic Valve Replacement. Artif Organs. 2018 Feb;42(2):E1-E12. doi: 10.1111/aor.13051. Epub 2017 Dec 11. PMID: 29226341.
     
  • Grieshaber P, Nink N, Roth P, Elzien M, Böning A, Koshty A. Endovascular treatment of the ascending aorta using a combined transapical and transfemoral approach. J Vasc Surg. 2018 Feb;67(2):649-655. doi: 10.1016/j.jvs.2017.10.046. Epub 2017 Nov 20. PMID: 29157681.

2017

  • Ennker J, Zadeh B, Pons-Kuehnemann J, Niemann B, Grieshaber P, Ennker IC, Boening A. Stentless Bioprostheses for Aortic Valve Replacement in Octogenarians: The Influence of Coronary Artery Disease. Thorac Cardiovasc Surg. 2018 Jun;66(4):322-327. doi: 10.1055/s-0037-1604048. Epub 2017 Jul 4. PMID: 28675910.
     
  • Lueck S, Mohr M, Werner C, Schmidt C, Malec E, Januszewska K. Temporary Tracheal Stenting After Pulmonary Artery Sling Repair in a Newborn. World J Pediatr Congenit Heart Surg. 2020 Jul;11(4):NP69-NP71. doi: 10.1177/2150135117713740. Epub 2017 Sep 21. PMID: 28933231.
     
  • Grieshaber P, Roth P, Oster L, Schneider TM, Görlach G, Nieman B, Böning A. Is delayed surgical revascularization in acute myocardial infarction useful or dangerous? New insights into an old problem. Interact Cardiovasc Thorac Surg. 2017 Nov 1;25(5):772-779. doi: 10.1093/icvts/ivx188. PMID: 28637179.
     
  • Grieshaber P, Nef H, Böning A, Niemann B. Myocardial Ischemia Caused by Subepicardial Hematoma. Thorac Cardiovasc Surg Rep. 2017 Jan;6(1):e5-e9. doi: 10.1055/s-0037-1601315. PMID: 28352501; PMCID: PMC5367147.

2016

  • Ennker J, Meilwes M, Pons-Kuehnemann J, Niemann B, Grieshaber P, Ennker IC, Boening A. Freestyle stentless bioprosthesis for aortic valve therapy: 17-year clinical results. Asian Cardiovasc Thorac Ann. 2016 Nov;24(9):868-874. doi: 10.1177/0218492316675244. Epub 2016 Oct 18. PMID: 27926465.
     
  • Grieshaber P, Lipp S, Arnold A, Görlach G, Wollbrück M, Roth P, Niemann B, Wilhelm J, Böning A. Impact of prophylactic administration of Levosimendan on short-term and long-term outcome in high-risk patients with severely reduced left-ventricular ejection fraction undergoing cardiac surgery - a retrospective analysis. J Cardiothorac Surg. 2016 Dec 1;11(1):162. doi: 10.1186/s13019-016-0556-2. PMID: 27906091; PMCID: PMC5131413.
     
  • Lueck S, Delis A, Minor T, Preusse CJ, Schaefer M. Age-related differences of intraischemic gap junction uncoupling in hearts during ischemia. J Thorac Cardiovasc Surg. 2016 Sep;152(3):729-36. doi: 10.1016/j.jtcvs.2016.04.069. Epub 2016 Apr 28. PMID: 27236865.
     
  • Lueck S, Sindermann J, Martens S, Scherer M. Mechanical circulatory support for patients with peripartum cardiomyopathy. J Artif Organs. 2016 Sep;19(3):305-9. doi: 10.1007/s10047-016-0891-z. Epub 2016 Mar 22. PMID: 27003430.

2015

  • Dell'Aquila AM, Lueck S, Ellger B. Surgeon's Tiredness or Patient's Fasting? What Is More Relevant for Outcome in Nonemergent Cardiac Surgery? Ann Thorac Surg. 2016 Apr;101(4):1633-4. doi: 10.1016/j.athoracsur.2015.09.092. PMID: 27000603.
  • Grieshaber P, Bakchoul T, Wilhelm J, Wagner A, Wollbrück M, Böning A, Sachs U. Platelet-activating protamine-heparin-antibodies lead to higher protamine demand in patients undergoing cardiac surgery. J Thorac Cardiovasc Surg. 2015 Oct;150(4):967-73.e1. doi: 10.1016/j.jtcvs.2015.07.057. Epub 2015 Jul 26. PMID: 26298870.

2014

  • Grieshaber P, Niemann B, Roth P, Böning A. Prophylactic intra-aortic balloon counterpulsation in cardiac surgery: it is time for clear evidence. Crit Care. 2014 Nov 29;18(6):662. doi: 10.1186/s13054-014-0662-2. PMID: 25673235; PMCID: PMC4331486.
     
  • Cabrera-Fuentes HA, Niemann B, Grieshaber P, Wollbrueck M, Gehron J, Preissner KT, Böning A. RNase1 as a potential mediator of remote ischaemic preconditioning for cardioprotection†. Eur J Cardiothorac Surg. 2015 Nov;48(5):732-7; discussion 737. doi: 10.1093/ejcts/ezu519. Epub 2015 Jan 5. PMID: 25564211.
     
  • Grieshaber P, Böning A. Prophylactic intra-aortic balloon counterpulsation in cardiac surgery: challenges in planning the "right" trial. Crit Care Med. 2014 Mar;42(3):e246-7. doi: 10.1097/CCM.0000000000000072. PMID: 24534985.


2013

  • Lueck S, Angeli E. Challenge of neonatal myocardial protection. Ann Thorac Surg. 2013 Dec;96(6):2286-7. doi: 10.1016/j.athoracsur.2013.05.039. PMID: 24296215.  
     
  • Lueck S, Preusse CJ, Welz A. Clinical relevance of HTK-induced hyponatremia. Ann Thorac Surg. 2013 May;95(5):1844-5. doi: 10.1016/j.athoracsur.2013.01.026. PMID: 23608285.
     
Sektion Kinderherzchirurgie

Universitätsklinikum Münster

Albert-Schweitzer-Campus 1, Gebäude A1

48149 Münster

+49 251 83 46102 

+49 251 83 46113

kinderherzchirurgie@ukmuenster.de